I will work mostly on two projects, linked by the common theme of controlling myopia (the focus of the Wildsoet Lab). One of my projects will involve guinea pigs as an animal model for myopia and will explore the influence of dosing on the effectiveness of atropine eye drops for slowing or preventing the development of myopia. The second project will involve human subjects and a study of anterior ocular changes induced by a specialized contact lens for myopia control.
Prof. Shapiro is an experimental particle physicist and a leader of the Lawrence Berkeley National Laboratory affiliated collider experiment known as: ATLAS collaboration at the CERN Large Hadron Collider (LHC). One of the most important pieces of the ATLAS research program is to search for new phenomena and interactions never before observed at the most basic level of nature. One class of theory that predicts such interactions is “Supersymmetry.” Samuel is working on the search for Supersymmetry in a special class of models where some of the Supersymmetric particles can propagate a measurable distance before decaying.
There are a couple of topics I am responsible for, including pollution economy, current U.S. healthcare system, China’s Belt and Road policy, etc. They are all very engaging and requires in-depth reading and research, which I learnt a lot from. I was not only analyzing the status quo, but was also responsible for proposing a hypothetical solution or version myself.
Prof. Feldman is leading the ECG2 project, a “Natural Language Understanding” system. Vivek is currently working with him on two projects, one to apply the natural language understanding system to control strategy video gaming, and another to build a healthcare-related question and answer system. This summer, Vivek wrote and submitted a paper to a conference about strategy video game control. He also made progress setting up the system for the healthcare project.
In low-income communities across the world, we have been observing an epidemic that is 100% preventable: tooth decay. Our in-depth analysis has repeatedly shown the correlation between poor oral health and malnutrition and our research aims to uncover the associated risk factors – junk food consumption and access, dental care access, oral health and nutrition education, mother’s education and feeding practices, family size, etc. I am interested in furthering our investigations by looking at the role of gender. What is the difference, if any, between tooth decay and malnutrition among girls and boys?
Autism spectrum disorder has a strong genetic basis. My research contributes to understanding the functions of the genes that are highly associated with autism. Main techniques employed include cloning, CRIPSR-Cas9 system to introduce gene mutation, phenotypical analysis using immunofluorescence and in situ hybridization.
I am currently assisting Professor Herd with conducting research on the influence of mass media –also known as “the super peer”– on alcohol consumption amongst African-American adolescents. We are specifically looking at popular movies from the Teen Media Study, which was conducted in 2001and 2002. Apart from this, I am also beginning a literature review, that looks at the film structure of the coming of age story when it is targeted towards a black audience.
For the summer, I’ve been working on the synthesis of a molecular linker that connects two different drug known as a PROTAC, or proteolysis targeting chimera. One drug at the end of this linker is a thalidomide derivative, which can bind to the E3 ubiquitin ligase cereblon (a protein in the cell that can mark other proteins for degradation). The other drug is a known suppressor of the YAP-TEAD complex in the cell, which is associated with hepatomegaly and tumorigenesis.
The research project focuses on migrants that return to Yucatan, Mexico. Specifically, it looks at their experiences in schools and with their families once they begin living in their hometowns. Through these experiences, the research will help us understand return migration in Mexico and transnational migration in the United States.
This study employs a number of important methodological features: experimental manipulation of stress, measurement of arousal using psychophysiological parameters, neurocognitive assessment of response inhibition, and behavioral indicators of whether response inhibition deficits translate to real world behavior. Much of the data collection has been completed over the past few semesters, and over the summer the main goal was to organize, clean, and analyze this data. We are hoping this research will fill major gaps in the literature by assessing the extent to which deficits in cognitive control resulting from heightened arousal is a mechanism driving the poor behavioral constraint associated with emotion-relevant impulsivity.